New Horizons in Science

Andrea Gore is exploring the surprisingly complex and important links between the brain and the endocrine system, especially reproductive hormones. She has found striking changes with age in neurons related to reproduction, perhaps explaining menopause and fertility declines in middle-aged men. And she has found that exposure to PCBs and other pollutants can profoundly disrupt reproduction. In one recent study, exposure of pregnant rats to the fungicide vinclozolin altered mating behavior in their great-grandchildren.